UNIVERSITY PARK, Pa. — The prevalence of the most abundant species of ticks found in Pennsylvania has shifted over the last century, according to Penn State scientists, who analyzed 117 years' worth of specimens and data submitted primarily by residents from around the state.
The researchers said understanding the spatial distribution patterns and host associations revealed by their analysis is important for assessing and reducing the risk of diseases caused by tickborne pathogens.
The Centers for Disease Control and Prevention reported a 3.5-fold increase in vectorborne diseases in the United States between 2004 and 2016, with more than 76 percent of cases caused by tickborne pathogens. The vast majority of these cases are attributed to Borrelia burgdorferi, the bacterial pathogen that causes Lyme disease. Pennsylvania has had the highest number of total Lyme disease cases in the United States since 2000.
Since the early 1900s, people have submitted ticks to the Penn State Department of Entomology and its forerunners for identification, and these specimens have become part of the collection of Penn State's Frost Entomological Museum, noted Joyce Sakamoto, assistant research professor of entomology in the College of Agricultural Sciences.
In the 1960s, the late entomology professor Robert Snetsinger ran a statewide media campaign to encourage tick submissions, and he received thousands from citizen scientists. He also conducted active surveillance, capturing and collecting ticks in the field.
Another Penn State entomologist, Steven Jacobs, a now-retired senior Extension associate, led a similar public service media campaign in the 1990s, resulting in another surge in tick submissions from citizens around the state.
The research team — Sakamoto, Jacobs and first author Damie Pak, doctoral candidate in biology — compiled data from more than 7,000 of these tick specimens dating from 1900 and analyzed the submissions for tick-community composition, host associations and spatio-temporal dynamics. Ticks were submitted from all 67 counties in Pennsylvania, and the specimens included 24 species.
More than 90 percent of submissions consisted of five species: Amblyomma americanum, lone star tick; Dermacentor variabilis, American dog tick; Ixodes cookei, groundhog tick or woodchuck tick; Ixodes scapularis, blacklegged tick; and Rhipicephalus sanguineus, brown dog tick.
"We found that based on these collections, there have been several shifts in the dominant species of ticks over the last 117 years," Sakamoto said.
Before 1990, the majority of tick submissions were identified as Ixodes cookei. Today, the dominant species is Ixodes scapularis, or blacklegged tick, which is the primary vector of Lyme disease.
“But this tick was almost nonexistent in Pennsylvania in the 1960s," Sakamoto said.
The researchers, who reported their results April 29 in Parasites & Vectors, said such changes in surveillance data can be correlated with climate change and variability; shifts in land use that can lead to habitat loss and fragmentation; and changes in human or animal behavior that may bring ticks and hosts into closer proximity.
Sakamoto explained that the blacklegged tick's population likely declined in the early 20th century because timber-harvesting practices such as clearcutting caused deforestation and destroyed habitat for deer and other wildlife that serve as hosts. As reforestation was achieved and habitat restored in the late 1900s, the population of these ticks — sometimes called deer ticks — exploded.
Blacklegged ticks now are found in every county in Pennsylvania, although the researchers' analysis suggests that their highest prevalence rates — per 100,000 people — occurred in northcentral Pennsylvania counties such as Elk, Forest and Cameron.
In addition to tick prevalence and geographic distribution, host-association data accompanying submitted tick specimens also can help in assessing risk, according to the researchers.
"Some species' common names are misleading because they imply only one host," Sakamoto said.
Ixodes cookei, the so-called groundhog tick, is really a generalist that also will feed on opossums, raccoons and other species — and may bite humans if given the opportunity. This tick also is a potentially important vector of Powassan encephalitis virus — a serious pathogen.
“So, commonly held misconceptions about tick-host associations may result in people underestimating or ignoring the risk," Sakamoto said.
The researchers conclude that the ideal tick surveillance program would employ both passive and active collection methods and would not focus solely on the most important "tick du jour," such as the current emphasis on the Lyme-carrying blacklegged tick.
"The consequences of neglecting other potential ticks of epidemiological significance include missing shifts in tick biodiversity, not monitoring range expansions of vectors, and not detecting the presence of introduced species, such as the Asian longhorned tick recently found in Pennsylvania,” Sakamoto said.